Pediatric Neurology is not just the little brother of Neurology. Children and adolescents have different diseases and problems than adults, disorders known in adulthood may present differentially in young patients. Children ask for different treatment options and show different courses and outcomes than adults with similar conditions.
Our research focuses on treatment, but in particular on neurological and neuropsychological sequelae of neuropediatric problems such as prematurity, cerebral palsy, traumatic brain injury, brain tumors and pediatric stroke. We investigate on factors that influence neurological and neuropsychological residual problems in these children and evaluate specific treatment options. We develop cognitive trainings and control for their effect on a neural level, but also in respect to the amelioration of everyday life of these children. We investigate neural reorganization mechanisms in children and adolescents after cancer, stroke and prematurity by means of transmagnetic stimulation (TMS), resting state functional MRI (rsfMRI), functional magnetic resonance imaging (fMRI) and arterial spin labeling (ASL). This allows us to strengthen the knowledge about neuroplastic processes in the developing brain and helps to tailor rehabilitation methods of these children to support their development.
Our research contributes to a better understanding of prognostic factors that are associated with outcome and enables the development of further therapeutic strategies for an optimal development of these children. Consequently, this will improve their quality of life, wellbeing and scholastic achievement and therefore adds to integration in adult social and professional life.
Stroke Registry: Swiss Neuropediatric Stroke Registry (SNPSR)A population based registry of pediatric stroke to analyze clinical outcome and neuroimaging aspect to improve knowledge and future management.
HERO Study: Hemispheric Reorganisation Study: We investigate functional reorganization processes in children after stroke by means of neurological and neuropsychological assessments, structural and resting state MRI and transcranial magnetic stimulation.
The Brainfit study aims to compare the effect of cognitive and sport activity training on brain structure, brain perfusion, cognition and quality of life in childhood cancer survivors. Collaboration with Children’s University Hospital in Zürich.